Description

TB-500 is a synthetic peptide representing a fragment of thymosin beta-4, a naturally occurring protein involved in cellular processes. It has been widely studied in preclinical and experimental models for its interaction with cell migration, actin regulation, and cytoskeletal organization pathways.

In research environments, TB-500 has been investigated for its role in cellular movement, structural protein dynamics, and peptide-mediated signaling mechanisms. Its ability to influence actin-binding processes makes it a valuable compound for studying cellular architecture and tissue-related biological pathways.

This peptide is commonly utilized in in vitro and laboratory-based research models focused on peptide signaling, cellular processes, and structural protein interactions.

Key Features:

Chemical Name: Thymosin Beta-4 Fragment (TB-500)
Molecular Formula: C₂₁₂H₃₅₀N₅₆O₇₈S
CAS Number: 77591-33-4
Amino Acid Sequence:
Ac-Lys-Lys-Asp-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-Gly-Arg-Asp-Ala-Pro-Ala-Asn-Gly

Physical Form: Lyophilized powder
Compound Class: Synthetic peptide / thymosin beta-4 fragment
Purity: ≥98% (HPLC)
Storage Conditions: Store at 36–46°F (2–8°C) in a dry, light-protected environment.

Common Research Pairings:

TB-500 is sometimes studied alongside other compounds in cellular and peptide signaling research, including:

• BPC-157 – investigated in cellular signaling and peptide pathway studies
• GHK-Cu – studied in extracellular matrix and gene expression research
• KPV – explored in peptide-mediated signaling pathways
• IGF-1 LR3 – examined in cellular signaling and growth factor research

These combinations are referenced strictly within controlled research environments to evaluate complementary biological mechanisms.

Research References:

• Goldstein, A. L. et al. (2005). Thymosin beta-4 and its role in cellular processes and actin regulation. Annals of the New York Academy of Sciences.
• Malinda, K. M. et al. (1999). Thymosin beta-4 and cell migration in experimental models. FASEB Journal.
• Huff, T. et al. (2001). The role of thymosin beta-4 in actin dynamics and cellular structure. Journal of Cell Science.

(References provided for informational and research context only.)

Important Notice:

This product is intended for research use only. It is not for human or veterinary use. It is not intended to diagnose, treat, cure, or prevent any disease. Use is restricted to qualified professionals in controlled laboratory environments.