Description

Sermorelin is a synthetic peptide corresponding to the first 29 amino acids of endogenous growth hormone-releasing hormone (GHRH 1-29). It has been widely studied in preclinical and experimental research for its interaction with pituitary GHRH receptors and its role in endocrine signaling pathways.

In research settings, Sermorelin has been investigated for its involvement in growth hormone regulation, receptor activation, and downstream signaling cascades. As a truncated analog of native GHRH, it is commonly utilized to study pulsatile hormone release patterns and peptide-receptor dynamics.

This peptide is frequently applied in in vitro and laboratory-based research models focused on endocrine system function, growth hormone pathways, and peptide-mediated signaling mechanisms.

Key Features:

Chemical Name: Growth Hormone-Releasing Hormone (1-29) Amide
Molecular Formula: C₁₄₉H₂₄₆N₄₄O₄₂
CAS Number: 86168-78-7
Amino Acid Sequence:
Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg

Physical Form: Lyophilized powder
Compound Class: Synthetic peptide / GHRH analog
Purity: ≥98% (HPLC)
Storage Conditions: Store at 36–46°F (2–8°C) in a dry, light-protected environment.

Common Research Pairings:

Sermorelin is sometimes studied alongside other compounds in endocrine and peptide signaling research, including:

• Ipamorelin – investigated in growth hormone secretagogue pathway studies
• GHRP-6 – studied in complementary ghrelin receptor signaling models
• IGF-1 LR3 – explored in downstream growth factor signaling research
• CJC-1295 (no DAC) – examined in GHRH analog comparison studies

These combinations are referenced strictly within controlled research environments to evaluate complementary biochemical mechanisms.

Research References:

• Thorner, M. O. et al. (1985). Growth hormone-releasing hormone and its analogs in endocrine research. Journal of Clinical Investigation.
• Gelato, M. C. et al. (1988). Effects of GHRH (1-29) on growth hormone secretion in experimental models. Journal of Clinical Endocrinology & Metabolism.
• Vance, M. L. et al. (1990). Pharmacological properties of GHRH analogs in research settings. Endocrine Reviews.

(References provided for informational and research context only.)

Important Notice:

This product is intended for research use only. It is not for human or veterinary use. It is not intended to diagnose, treat, cure, or prevent any disease. Use is restricted to qualified professionals in controlled laboratory environments.