Description

Product Description:

NAD⁺ (Nicotinamide Adenine Dinucleotide) is a naturally occurring coenzyme present in all living cells, playing a critical role in cellular energy production and redox reactions. It functions as a key electron carrier in metabolic processes, particularly within mitochondrial pathways and ATP generation.

In preclinical and experimental research settings, NAD⁺ has been widely studied for its involvement in oxidative phosphorylation, enzymatic activity, and cellular signaling pathways, including interactions with sirtuins and PARP enzymes. These pathways are central to studies focused on cellular metabolism, DNA repair mechanisms, and mitochondrial biology.

Due to its essential role in cellular function, NAD⁺ is commonly utilized in in vitro and laboratory-based research models examining energy metabolism, redox balance, and biochemical pathway regulation.

Key Features:

Chemical Name: Nicotinamide Adenine Dinucleotide (NAD⁺)
Molecular Formula: C₂₁H₂₇N₇O₁₄P₂
CAS Number: 53-84-9
Structure: Dinucleotide coenzyme (oxidized form)
Physical Form: Lyophilized powder
Compound Class: Coenzyme / endogenous metabolic compound
Purity: ≥98% (HPLC)
Storage Conditions: Store at 36–46°F (2–8°C) in a dry, light-protected environment.

Common Research Pairings:

NAD⁺ is sometimes studied alongside other compounds in metabolic and cellular research, including:

• Glutathione – investigated in redox balance and antioxidant pathway studies
• MOTS-c – studied in mitochondrial signaling and energy regulation models
• 5-Amino-1MQ – explored in enzymatic and metabolic pathway research
• Alpha Lipoic Acid (ALA) – examined in mitochondrial and oxidative processes

These combinations are referenced strictly within controlled research environments to evaluate complementary biochemical mechanisms.

Research References:

• Verdin, E. (2015). NAD⁺ in aging, metabolism, and neurodegeneration research. Science.
• Yoshino, J. et al. (2018). NAD⁺ metabolism and its role in cellular function. Cell Metabolism.
• Canto, C. et al. (2015). NAD⁺ metabolism and mitochondrial function. Cell Metabolism.

(References provided for informational and research context only.)

Important Notice:

This product is intended for research use only. It is not for human or veterinary use. It is not intended to diagnose, treat, cure, or prevent any disease. Use is restricted to qualified professionals in controlled laboratory environments.