Product Description:

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a naturally occurring peptide encoded within mitochondrial DNA. It has been studied in preclinical and experimental models for its interaction with cellular energy regulation, metabolic signaling, and mitochondrial communication pathways.In research settings, MOTS-c has been investigated for its role in AMPK activation, glucose metabolism, and adaptive cellular responses to metabolic stress. Its mitochondrial origin distinguishes it from many other peptides, making it a valuable compound for studying mitochondrial signaling, energy homeostasis, and cellular adaptation mechanisms.This peptide is commonly utilized in in vitro and laboratory-based research models focused on metabolic processes, mitochondrial biology, and peptide-mediated signaling networks.

Key Features:

Chemical Name: MOTS-c (Mitochondrial-Derived Peptide)
Molecular Formula: C₁₀₁H₁₅₂N₂₈O₂₂S₂
CAS Number: 1627580-64-6
Amino Acid Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
Physical Form: Lyophilized powder
Compound Class: Mitochondrial-derived peptide
Purity: ≥98% (HPLC)
Storage Conditions: Store at 36–46°F (2–8°C) in a dry, light-protected environment.

Common Research Pairings:

MOTS-c is sometimes studied alongside other compounds in metabolic and cellular research, including:

• 5-Amino-1MQ – investigated in metabolic enzyme pathway studies
• GLP-1 receptor agonists – studied in metabolic signaling models
• AOD-9604 – explored in energy regulation research
• Glutathione – examined in mitochondrial and redox pathway studies

These combinations are referenced strictly within controlled research environments to evaluate complementary biological mechanisms.

Research References:

• Lee, C. et al. (2015). The mitochondrial-derived peptide MOTS-c regulates metabolic homeostasis. Cell Metabolism.
• Kim, S. J. et al. (2018). MOTS-c and its role in metabolic adaptation and AMPK activation. Nature Communications.
• Reynolds, J. C. et al. (2021). Mitochondrial peptides and their role in cellular signaling pathways. Trends in Endocrinology & Metabolism.

(References provided for informational and research context only.)

Important Notice:

This product is intended for research use only. It is not for human or veterinary use. It is not intended to diagnose, treat, cure, or prevent any disease. Use is restricted to qualified professionals in controlled laboratory environments.