Description

Product Description:

Kisspeptin-10 is a synthetic decapeptide corresponding to amino acids 45–54 of the endogenous peptide kisspeptin, also known as metastin. It is a biologically active fragment that has been widely studied for its interaction with the GPR54 (KISS1R) receptor, a key regulator of neuroendocrine signaling.

In preclinical and experimental research settings, Kisspeptin-10 has been investigated for its role in hypothalamic-pituitary-gonadal (HPG) axis signaling, making it a valuable compound in studies focused on reproductive hormone regulation and neuroendocrine pathway activity.

This peptide is commonly utilized in in vitro and laboratory-based research models examining receptor activation, hormonal signaling cascades, and peptide-mediated endocrine processes.

Key Features:

Chemical Name: Kisspeptin-10 / Metastin (45-54)
Molecular Formula: C₆₃H₈₃N₁₇O₁₄
CAS Number: 374675-21-5
Amino Acid Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂
Physical Form: Lyophilized powder
Compound Class: Synthetic peptide / neuroendocrine signaling peptide
Purity: ≥98% (HPLC)
Storage Conditions: Store at 36–46°F (2–8°C) in a dry, light-protected environment.

Common Research Pairings:

Kisspeptin-10 is sometimes studied alongside other compounds in endocrine and neurobiological research, including:

• GnRH (Gonadotropin-Releasing Hormone) – investigated in HPG axis signaling studies
• CJC-1295 & Ipamorelin – explored in broader endocrine pathway research
• IGF-1 LR3 – studied in downstream hormonal signaling models
• Melanotan II – examined in neuropeptide and receptor interaction studies

These combinations are referenced strictly within controlled research environments to evaluate complementary biochemical mechanisms.

Research References:

• Kotani, M. et al. (2001). The metastasis suppressor gene KISS1 encodes kisspeptins, ligands of the GPR54 receptor. Journal of Biological Chemistry.
• Seminara, S. B. et al. (2003). The GPR54 gene and its role in reproductive hormone regulation. New England Journal of Medicine.
• Dhillo, W. S. et al. (2005). Kisspeptin-10 and its effects on neuroendocrine signaling in experimental models. Journal of Clinical Endocrinology & Metabolism.

(References provided for informational and research context only.)

Important Notice:

This product is intended for research use only. It is not for human or veterinary use. It is not intended to diagnose, treat, cure, or prevent any disease. Use is restricted to qualified professionals in controlled laboratory environments.