Description

Product Description:

Melanotan II (MT-2) is a synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH). It has been widely studied in preclinical and experimental models for its interaction with melanocortin receptors (MC1R, MC3R, MC4R, and MC5R), which are involved in various physiological signaling pathways.

In research settings, Melanotan II has been investigated for its role in melanocortin receptor activation, peptide-mediated signaling, and neuroendocrine pathway interactions. Its structural modifications provide enhanced stability compared to endogenous α-MSH, making it a useful compound for studying receptor binding and downstream signaling mechanisms.

This peptide is commonly utilized in in vitro and laboratory-based research models focused on receptor pharmacology, peptide signaling, and neuroendocrine system dynamics.

Key Features:

Chemical Name: Melanotan II
Molecular Formula: C₅₀H₆₉N₁₅O₉
CAS Number: 121062-08-6
Amino Acid Sequence: Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂
Physical Form: Lyophilized powder
Compound Class: Synthetic peptide / melanocortin receptor agonist
Purity: ≥98% (HPLC)
Storage Conditions: Store at 36–46°F (2–8°C) in a dry, light-protected environment.

Common Research Pairings:

Melanotan II is sometimes studied alongside other compounds in peptide and neuroendocrine research, including:

• KPV – investigated in melanocortin-related signaling pathways
• Kisspeptin-10 – studied in neuroendocrine signaling research
• CJC-1295 & Ipamorelin – explored in broader endocrine pathway studies
• PT-141 (Bremelanotide) – examined in melanocortin receptor subtype research

These combinations are referenced strictly within controlled research environments to evaluate complementary biological mechanisms.

Research References:

• Hadley, M. E. et al. (1998). Melanocortin peptides and receptor interactions in biological systems. Annals of the New York Academy of Sciences.
• Hruby, V. J. et al. (2001). Design and structure-activity relationships of melanocortin receptor agonists. Journal of Medicinal Chemistry.
• Wessells, H. et al. (2000). Melanocortin receptor agonists in neuroendocrine research. Journal of Urology.

(References provided for informational and research context only.)

Important Notice:

This product is intended for research use only. It is not for human or veterinary use. It is not intended to diagnose, treat, cure, or prevent any disease. Use is restricted to qualified professionals in controlled laboratory environments.